This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.

Dettagli prodotto

• Codice: AN004770P_1mg
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
• Isotipo: Mouse IgG1, κ
• Clonalità: Monoclonal
• Clone: DREG.55
• Applicazione: FCM
• Simbolo target: Leukocyte adhesion molecule;Leukocyte surface antigen Leu;Leukocyte-endothelial cell adhesion molecule;LECAM;LAM;LEU;SELL;CD62L;LAM1;LECAM1;LEU8;LNHR;LSEL;LYAM1;PLNHR;TQ1;CD62 antigen-like family member L;CD62antigen-likefamilymemberL;gp90-MEL;LAM-1;Leu-8;Leukocyte adhesion molecule 1;Leukocyte surface antigen Leu-8;Leukocyte-endothelial cell adhesion molecule 1;L-selectin;Ly22;Ly-22;Lyam-1;Lymph node homing receptor;Lymphnodehomingreceptor;6&apos- sulfated Lewis X-X; LECAM-1; LAM-1
• Area di ricerca: Cardiovascular;Immunology;Stem Cells