The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to geneRate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

Dettagli prodotto

• Codice: AN007530P_25μg
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
• Isotipo: Mouse IgG1, κ
• Clonalità: Monoclonal
• Clone: IIA1
• Applicazione: FCM
• Simbolo target: VLA;ITGA;CD49e;FNRA;VLA-5;VLA5A;Integrin alpha 5;ITGA5;CD49 Antigen-Like Family Member E;Fibronectin Receptor Subunit Alpha;Integrin Alpha-5;Integrin Alpha-F; &alpha-5 integrin-n;VLA-5αalpha 5 (fibronectin receptor;alpha polypeptide);alpha subunit;Fibronectin receptor;Integrin;Integrin alpha 5 (fibronectin receptor alpha);Integrin alpha-5 light chain;ITA5;Very late activation protein 5;VLA5
• Area di ricerca: Signal Transduction;Stem Cells