This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms.

Dettagli prodotto

• Codice: AN007920P_1mg
• Marca: Elabscience
• Specie target: Human
• Host: Rat
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
• Isotipo: Rat IgG2b,κ
• Clonalità: Monoclonal
• Clone: 237920
• Applicazione: FCM
• Simbolo target: Triggering receptor expressed on monocytes;Triggering receptor expressed on myeloid cells;TREM2;TREM-2;Trem2a;Trem2b;Trem2c;Triggering receptor expressed on monocytes 2;Triggering receptor expressed on myeloid cells 2
• Area di ricerca: Immunology