CD35, also known as complement receptor 1 (CR1), is a 220-300 kDa N-glycosylated member of the RCA (regulators of complement activation) family of proteins. CD35 binds and internalizes particles and immune complexes that are opsonized with MBL or complement components C3b, C3i, C4b, or C1q. CD35 additionally protects the cell from complement-mediated lysis by serving as a cofactor for Factor I and inhibiting the C3 and C5 convertases. The extracellular domain (ECD) of human CD35 contains 30 tandem SCR/SUSHI repeats.

Codice: E-AB-F1062A_100mg | Marca: Elabscience | Confezionamento: 100mg

Specie: HumanIsotipo: Mouse IgG1, κClone: E11

Recombinant Human CD35 protein

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Codice: E-AB-F1062A_100mg
Marca: Elabscience
Specie target: Human
Host: Mouse
Concentrazione: ≥ 1 mg/mL
Link: Apri link
Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Isotipo: Mouse IgG1, κ
Clonalità: Monoclonal
Clone: E11
Applicazione: FCM
Simbolo target: C3BR;C3b/C4b receptor;CD35;CR1;Complement receptor type 1
Area di ricerca: Cell Biology;Complement;Immunology;Neuroinflammation;Neuroscience

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