The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

Dettagli prodotto

• Codice: E-AB-F11400P_1mg
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
• Isotipo: Mouse IgG1, κ
• Clonalità: Monoclonal
• Clone: O323
• Applicazione: FCM
• Simbolo target: S152. LPFS;T-cell activation antigen CD;TNFRSF;S152.LPFS;CD27;S152;S152. LPFS2;T14;TNFRSF7;Tp55;S152.LPFS2;CD27L receptor;T-cell activation antigen CD27; S152; TNFRSF7;CD 27;CD27 antigen;CD27 molecule;LPFS2;MGC20393;OTTHUMP00000238557;T cell activation antigen CD27;T cell antivation antigen S152;TNFRSF 7;TNFSF7;Tp 55;Tumor necrosis factor receptor superfamily member 7
• Area di ricerca: Immunology;Cancer;Stem Cells