This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

Dettagli prodotto

• Codice: E-AB-F1150A_100mg
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
• Isotipo: Mouse IgG1, κ
• Clonalità: Monoclonal
• Clone: 104D2
• Applicazione: FCM
• Simbolo target: KIT;C-Kit;CD117;PBT;SCFR;Mast/stem cell growth factor receptor Kit;p145 c-kit;Piebald trait protein;Proto-oncogene c-Kit;Tyrosine-protein kinase Kit;v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog;SCFR;C Kit;CD_antigen: CD117;c-Kit Ligand;Kit Ligand;KIT oncogene;KIT proto oncogene receptor tyrosine kinase;KIT proto-oncogene receptor tyrosine kinase;Mast cell growth factor receptor;MGF;Proto oncogene c Kit;Proto oncogene tyrosine protein kinase Kit;SCF Receptor;soluble KIT variant 1;Steel Factor Receptor;Stem cell factor receptor;tyrosine protein kinase Kit;v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog;v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein
• Area di ricerca: Immunology;Tags & Cell Markers;Signal Transduction;Neuroscience;Stem Cells;Cancer;Developmental Biology