High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.

Dettagli prodotto

• Codice: E-AB-F1366A_5mg
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
• Isotipo: Mouse IgG1, κ
• Clonalità: Monoclonal
• Clone: L291H4
• Applicazione: FCM
• Simbolo target: CCR;CKR;MGC;HGCN;CMKBR;ChemR;CC-CKR;CC-CKR-4;ChemR13;CKR4;HGCN:14099;K5-5;MGC88293;CMKBR4;CCR4;C-C motif chemokine receptor 4;CD194
• Area di ricerca: Immunology;Cardiovascular