CD1a is a 49 kDa transmembrane glycoprotein in the CD1 family of glycolipid antigen-presenting MHC-like molecules. CD1a contains one Ig-like domain in its extracellular region. It is expressed by most nonhuman mammals but not by mice or rats. Complexes of CD1a with beta 2-microglobulin and endogenous glycolipids are constitutively expressed on antigen presenting cells, cortical thymocytes, and Langerhans cells. CD1a is a target of autoreactive Th22 helper T cells in the skin.

Dettagli prodotto

• Codice: E-AB-F13730P_25mg
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
• Isotipo: Mouse IgG1, κ
• Clonalità: Monoclonal
• Clone: Ab571
• Applicazione: FCM
• Simbolo target: FCB;HTA;T-cell surface antigen T6/Leu;CD1A;CD1;FCB6;HTA1;R4;T6;CD 1a;T-cell surface glycoprotein CD1a;T-cell surface antigen T6/Leu-6; T6; HTA1;a polypeptide;CD1A Antigen;CD1a molecule;cluster of differentiation 1 A;cortical thymocyte antigen CD1A;differentiation antigen CD1 alpha 3;epidermal dendritic cell marker CD1a;FCB 6;HTA 1;hTa1 thymocyte antigen;OTTHUMP00000018907;R 4;T 6
• Area di ricerca: Immunology