This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.
Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Simbolo target: CCL17 SCYA17 TARC
Ig target: A-152E5.3;A152E53;ABCD 2;ABCD2;C-C motif chemokine 17;CC chemokine TARC;CCL17;CCL17;Chemokine CC Motif Ligand 17;MGC138271;MGC138273;SCYA17;Small Inducible Cytokine A17;Small Inducible Cytokine A17 Precursor;Small Inducible Cytokine Subfamily A (Cys Cys);Small Inducible Cytokine Subfamily A (Cys Cys) Member 17;Small-inducible cytokine A17;T Cell Directed CC Chemokine;Thymus and activation regulated chemokine;Thymus and activation-regulated chemokine
Area di ricerca:Cancer;Immunology
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