The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13.

Dettagli prodotto

• Codice: PDEH100498_100μg
• Marca: Elabscience
• Specie target: Human
• Host: E.coli
• Confezionamento: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Simbolo target: STAR
• Ig target: Cholesterol trafficker;Luteinizing hormone induced protein;mitochondrial;Mitochondrial steroid acute regulatory protein;StAR;StAR related lipid transfer (START) domain containing 1;STAR;StARD1;START domain containing 1;START domain containing protein 1;START domain-containing protein 1;Steroid acute regulatory protein;Steroidogenic acute regulator;Steroidogenic acute regulatory protein;Steroidogenic acute regulatory protein mitochondrial
• Area di ricerca: Signal Transduction;Cancer;Metabolism