The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.
MAP1LC3B (Microtubule Associated Protein 1 Light Chain 3 Beta) is a Protein Coding gene. Diseases associated with MAP1LC3B include Sporadic Pheochromocytoma and Lacrimal Gland Adenocarcinoma. Among its related pathways are Vesicle-mediated transport and Senescence and Autophagy in Cancer. GO annotations related to this gene include microtubule binding. An important paralog of this gene is MAP1LC3B2.
Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Simbolo target: MAP1LC3B
Ig target: ATG8F;Autophagy-related protein LC3 B;Autophagy-related ubiquitin-like modifier LC3 B;LC3B;LC3II;MAP1 light chain 3 like protein 2;MAP1 light chain 3-like protein 2;MAP1A/1BLC3;MAP1A/MAP1B LC3 B;MAP1A/MAP1B light chain 3 B;MAP1ALC3;MAP1LC3B a;Map1lc3b;Microtubule associated protein 1 light chain 3 beta;Microtubule-associated protein 1 light chain 3 beta;Microtubule-associated proteins 1A/1B light chain 3B;MLP3B
Area di ricerca:Signal Transduction;Neuroscience;Cardiovascular;Cancer;Metabolism
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