Chemokine (C-X-C Motif) Ligand 9 (CXCL9) belongs to the intercrine alpha (chemokine CXC) family. It is secreted by interferon stimulated monocytes, macrophages and endothelial cells, which elicits chemotactic functions by interacting with the chemokine receptor CXCR3. CXCL9 acts as a Th1 (type 1 helper T) cell chemoattractant and plays a role in the growth, activation and movement of cells associated with immune and inflammatory responses, and in tumour growth inhibition. It is closely related to two other CXC chemokines called CXCL10 and CXCL11, whose genes are located near the gene for CXCL9 on human chromosome 4.
Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Simbolo target: CXCL9
Ig target: crg;CXCL;SCYB;C-X-C Motif Chemokine;Small-Inducible Cytokine B;Chemokine(C-X-C motif) ligand;CXCL9;CMK;Humig;MIG;SCYB9;crg-10;Chemokine(C-X-C motif) ligand 9;C-X-C Motif Chemokine 9;Gamma-Interferon-Induced Monokine;Monokine induced by gamma interferon;Monokine Induced by Interferon-Gamma;Monokine Induced by Interferon-γ;Small-Inducible Cytokine B9
Area di ricerca:Immunology
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