Prostaglandin-H2 D-Isomerase (PTGDS) belongs to the Lipocalin family of calycin superfamily. PTGDS is preferentially expressed in the brain. PTGDS catalyzes the conversion of PGH2 to PGD2; a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. PTGDS is involved in a variety of CNS functions; such as sedation; REM sleep and PGE2-induced allodynia; and may have an anti-apoptotic role in oligodendrocytes. PTGDS binds small non-substrate lipophilic molecules and may act as a scavenger for harmful hydrophopic molecules and a secretory retinoid and thyroid hormone transporter. It possibly participates in development and maintenance of the blood-brain; blood-retina; blood-aqueous humor; blood-testis barrier; the central nervous system and male reproductive system.

Codice: PKSH030653_50μg | Marca: Elabscience | Confezionamento: 50μg

Specie: Human

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Codice: PKSH030653_50μg
Marca: Elabscience
Specie target: Human
Host: HEK293 Cells
Confezionamento: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5.
Link: Apri link
Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Simbolo target: PGD2 Synthase;PTGDS
Ig target: Beta-Trace Protein;Cerebrin-28;Glutathione-Independent PGD Synthase;Lipocalin-Type Prostaglandin-D Synthase;PDS;PGD2 Synthase;PGDS;PGDS2;PTGDS;Prostaglandin D Synthase;Prostaglandin-D2 Synthase;Prostaglandin-H2 D-Isomerase
Area di ricerca: Signal Transduction;

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