Secretory leukoprotease inhibitor (SLPI); also called antileukoprotease (ALP); is a 12-kDa; nonglycosylated serine protease inhibitor present in mucous secretions. It is thought to play a role in protecting the mucosae from injury associated with inflammation. SLPI is locally produced by serous cells; including bronchial submucosal glands. Elafin and SLPI are members of larger families of proteins secreted predominantly at mucosal sites; and have been shown to be modulated in multiple pathological conditions. Elafin and SLPI are structurally related in that both have a fold with a four-disulfide core or whey acidic protein (WAP) domain responsible for inhibiting proteases. SLPI is a prominent innate immune protein of the respiratory tract; possessing serine protease inhibitor activity; antibacterial activity; and anti-inflammatory/immunomodulatory activity.

Codice: PKSH031665_100μg | Marca: Elabscience | Confezionamento: 100μg

Specie: Human

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Codice: PKSH031665_100μg
Marca: Elabscience
Specie target: Human
Host: Baculovirus-Insect Cells
Confezionamento: Lyophilized from sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 7.4 <br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
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Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Applicazione: Enzyme
Ig target: ALK1;ALP;BLPI;HUSI;HUSI-I;MPI;WAP4;WFDC4
Area di ricerca: Cell biology;Cardiovascular;immunology

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