Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1) is a member of interleukin-1 receptor family. The protein structurally comprises three extracellular immunoglobulin domains; which presumably mediate binding of an as yet unidentified ligand; a transmembrane region; and an intracellular domain; which is likely to enable signalling via the NFkB pathway. The means of signalling is almost certain to be identical to that used by the IL1R family and the more distally related Toll protein. L1RAPL1 protein physically interacts via its 150 aa C-terminal domain with neuronal calcium sensor-1 (NCS-1); a protein widely expressed in neurons and the related chromaffin and PC12 cells. IL1RAPL1 is an integral membrane protein responsible for a nonsyndromic form of mental retardation (MR). It is suggested to affect human cognitive ability to some extent; especially the memory and concentration capability.

Codice: PKSH031795_100μg | Marca: Elabscience | Confezionamento: 100μg

Specie: Human

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Codice: PKSH031795_100μg
Marca: Elabscience
Specie target: Human
Host: HEK293 Cells
Confezionamento: Lyophilized from sterile PBS, pH 7.4<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
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Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Simbolo target: IL-1R8/IL1RAPL1
Ig target: IL1R;OPHN;TIGIRR;MRX;IL1RAPL1;IL1R8;IL1RAPL;MRX10;MRX21;MRX34;OPHN4;TIGIRR-2;IL1RAPL-1;IL-1RAPL-1;IL-1-RAPL-1;Interleukin-1 Receptor Accessory Protein-Like 1;Oligophrenin-4;Three Immunoglobulin Domain-Containing IL-1 Receptor-Related 2;X-Linked Interleukin-1 Receptor Accessory Protein-Like 1
Area di ricerca: Neuroscience

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