Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in Glutathione Synthetase can also cause the glutathione synthetase deficiency of erythrocytes, which is a mild form causing hemolytic anemia.

Codice: PKSH032497_50μg | Marca: Elabscience | Confezionamento: 50μg

Specie: Human
Dettagli prodotto
  • Codice: PKSH032497_50μg
  • Marca: Elabscience
  • Specie target: Human
  • Host: E.coli
  • Confezionamento: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM NaCl, pH 7.5.
  • Link: Apri link
  • Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Simbolo target: GSS
  • Ig target: GSH Synthetase;GSH-S;GSS;Glutathione Synthase;Glutathione Synthetase
  • Area di ricerca: Signal Transduction;Cell biology;Neuroscience;metabolism;