Ubiquitin Carboxyl-Terminal Hydrolases (UCHs) are a family of cysteine hydrolases. They catalyze the hydrolysis of amides, thioesters and esters, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin. Up regulation of UCHL3 is associated with uterine cervical neoplasms. UCHL3 is implicated in age related cognitive disorders. UCHL3 also promotes adipogenesis and insulin signaling. In mice, UCHL3 knockout have been shown to be resistant to diet-induced obesity.

Codice: PKSH033176_10μg | Marca: Elabscience | Confezionamento: 10μg

Specie: Human

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Codice: PKSH033176_10μg
Marca: Elabscience
Specie target: Human
Host: E.coli
Confezionamento: Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, 150mM NaCl, 1mM DTT, 50% Glycerol, pH 8.0.
Link: Apri link
Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Simbolo target: UCHL3;UCH-L3
Ig target: UCH-L3;UCHL3;Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L3;Ubiquitin Thioesterase L3
Area di ricerca: Cell biology;epigenetics and nuclear signal

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