Ubiquitin-Conjugating Enzyme E2 B (UBE2B) belongs to the ubiquitin-conjugating enzyme family. UBE2B can catalyze the covalent attachment of ubiquitin to other proteins; and is essential for the multi-ubiquitination and degradation of N-end rule substrates. UBE2B is indispensability for postreplication repair of UV-damaged DNA and may be involved in neurite outgrowth.Additionally; UBE2B may have a role in sepsis-induced muscle protein proteolysis and cancer-induced cachexia.

Dettagli prodotto

• Codice: PKSH033179_50μg
• Marca: Elabscience
• Specie target: Human
• Host: E.coli
• Confezionamento: Supplied as a 0.2 μm filtered solution of 10mM HEPES, pH 7.5.
• Link: Apri link
• Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
• Simbolo target: UBE2B;HR6B
• Ig target: HR6B;RAD6 Homolog B;RAD6B;UBE2B;Ubiquitin Carrier Protein B;Ubiquitin-Conjugating Enzyme E2 B;Ubiquitin-Conjugating Enzyme E2-17 kDa;Ubiquitin-Protein Ligase B;hHR6B
• Area di ricerca: Cell biology;Cancer;epigenetics and nuclear signal;metabolism