Ubiquitin-Conjugating Enzyme E2 S (UBE2S) is a member of the Ubiquitin-Conjugating Enzyme family. UBE2S interacts with CDC20, FZR1/CDH1 and VHL. UBE2S can form a thiol ester linkage with Ubiquitin in an Ubiquitin Activating Enzyme-Dependent manner, a characteristic property of Ubiquitin Carrier Proteins. UBE2S acts as an essential factor of the Anaphase Promoting Complex/Cyclosome, a cell cycle-regulated Ubiquitin ligase that controls progression through mitosis. UBE2S is also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A.

Codice: PKSH033189_10μg | Marca: Elabscience | Confezionamento: 10μg

Specie: Human

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Codice: PKSH033189_10μg
Marca: Elabscience
Specie target: Human
Host: E.coli
Confezionamento: Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5.
Link: Apri link
Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Simbolo target: UBE2S
Ig target: E2-EPF;E2EPF;UBE2S;Ubiquitin Carrier Protein S;Ubiquitin-Conjugating Enzyme E2 S;Ubiquitin-Conjugating Enzyme E2-24 kDa;Ubiquitin-Conjugating Enzyme E2-EPF5;Ubiquitin-Protein Ligase S
Area di ricerca: epigenetics and nuclear signal

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