Tripeptidyl-Peptidase 1 (TPP1) belongs to the peptidase S53 family. TPP1 is detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues. TPP1 is lysosomal serine protease with tripeptidyl-peptidase I activity. TPP1 may act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. TPP1 requires substrates with an unsubstituted N-terminus. TPP1 mutations have also been shown to cause neuronal ceroid lipofuscinosis type 2 (CLN2).

Codice: PKSH033493_10μg | Marca: Elabscience | Confezionamento: 10μg

Specie: Human

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Codice: PKSH033493_10μg
Marca: Elabscience
Specie target: Human
Host: HEK293 Cells
Confezionamento: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM CaCl<sub>2</sub>, 10% Glycerol, pH 7.5.
Link: Apri link
Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Simbolo target: TPP1;CLN2
Ig target: CLN2;Cell Growth-Inhibiting Gene 1 Protein;GIG1;LPIC;Lysosomal Pepstatin-Insensitive Protease;SCAR7;TPP-1;TPP1;Tripeptidyl Aminopeptidase;Tripeptidyl-Peptidase 1
Area di ricerca: Cell biology;Neuroscience

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