Matrix metalloproteinase-7 proenzyme (proMMP-7) is a 30.47 kDa matrix metalloproteinases with 273 amino acid residues. MMP-7 restricted production by normal mucosal and exocrine gland epithelial cells, as well as by carcinoma cells. Functionally, it involved breakdown of extracellular matrix (casein, gelatins of types I, III, IV, and V, and fibronectin) in normal physiological processes and disease processes. MMP-7 is contributed to early tumor development during carcinogenesis. proMMP7 activation by trypsin occurs via an intermediate cleaved at Lys50-Asn51.

Dettagli prodotto

• Codice: PKSH034171_20μg
• Marca: Elabscience
• Specie target: Human
• Host: E.coli
• Confezionamento: Lyophilized from sterile PBS,pH 8.0.<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Simbolo target: MMP7
• Ig target: MMP-7;MPSL1;PUMP-1
• Area di ricerca: Cardiovascular Signal Transduction Cancer Cell Biology