Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Codice: PKSM041035_50μg | Marca: Elabscience | Confezionamento: 50μg

Specie: Mouse

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Codice: PKSM041035_50μg
Marca: Elabscience
Specie target: Mouse
Host: HEK293 Cells
Confezionamento: Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Link: Apri link
Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Simbolo target: Granzyme B;GZMB
Ig target: CCP1;CTLA-1;Ctla-1;Ctla1;Cytotoxic cell protease 1;Fragmentin-2;Granzyme B(G,H);Gzmb

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