Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament (F-actin)-binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It may also play important roles in cell morphology and locomotion. Vinculin is a 117-kDa,1,066-amino-acid protein which is ubiquitously expressed. Its splice variant,metavinculin (124 kDa),is muscle-specific.

Dettagli prodotto

• Codice: AN00297M_25μL
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles. Protected from prolonged exposure to light.
• Isotipo: IgG1
• Clonalità: Monoclonal
• Clone: 4D4
• Coniugazione: Elab Fluor®647
• Applicazione: FCM
• Diluizione: FCM 0.2 µg per 10^6 cells in a 100 µL suspension
• Simbolo target: Vinculin
• Ig target: Vinculin;Metavinculin (MV);VCL
• Area di ricerca: Signal Transduction;Tags and Cell Markers;Isotype/Loading;Controls;Neuroscience;Biochemicals;Cancer;Cardiovascular;Cell Biology;Immunology;Metabolism;Epigenetics and Nuclear Signaling;Stem Cells