This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Dettagli prodotto

• Codice: AN200018P_100μL
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
• Isotipo: IgG1
• Clonalità: Monoclonal
• Clone: 8D1
• Coniugazione: Unconjugated
• Applicazione: ICC/IF
• Diluizione: ICC/IF 1:20-1:100;
• Simbolo target: AFP
• Ig target: AFPD;FETA;HPAFP;AFP;Alpha fetoglobulin;Alpha fetoprotein;Alpha fetoprotein precursor;Alpha-1-fetoprotein;Alpha-fetoglobulin;Alpha-fetoprotein;Hereditary persistence of;Hereditary persistence of alpha fetoprotein;included;oralpha fetal protein
• Area di ricerca: Cardiovascular;Cancer;Developmental Biology;Kits;Lysates;Other