The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.
Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotipo: IgG2b
Clonalità: Monoclonal
Clone: 8D9
Coniugazione: Unconjugated
Applicazione: WB;FCM;IP
Diluizione: WB 1:500-1:1000;FCM 1:100-1:500;IP 0.2-1 μL/mg of lysate
Simbolo target: SOD1
Ig target: hSod;HEL-S;SOD1;ALS;ALS1;HEL-S-44;IPOA;SOD;hSod1;homodimer;Superoxide dismutase [Cu-Zn];Amyotrophic lateral sclerosis 1 adult;Cu/Zn SOD;Cu/Zn superoxide dismutase;Epididymis secretory protein Li 44;HEL S 44;Indophenoloxidase A;Mn superoxide dismutase;SOD soluble;SOD2;SODC;Superoxide dismutase 1;Superoxide dismutase 1 soluble;Superoxide dismutase Cu Zn;Superoxide dismutase cystolic
Area di ricerca:Signal Transduction;Cell Biology;Cancer;Metabolism
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