The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM24, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder.

Dettagli prodotto

• Codice: AN200056P_100μL
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
• Isotipo: IgG2a
• Clonalità: Monoclonal
• Clone: 9D5
• Coniugazione: Unconjugated
• Applicazione: IHC-P
• Diluizione: IHC-P 1:50-1:200;
• Simbolo target: USP7
• Ig target: TEF;USP;USP7;HAUSP;TEF1
• Area di ricerca: Cell Biology;Microbiology;Cancer;Epigenetics and Nuclear Signaling