Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-0 activation.

Dettagli prodotto

• Codice: AN200068P_100μL
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
• Isotipo: IgG2b
• Clonalità: Monoclonal
• Clone: 3G7
• Coniugazione: Unconjugated
• Applicazione: IHC-P
• Diluizione: IHC-P 1:1000-1:20000;
• Simbolo target: TNFAIP8
• Ig target: GG2;SCCS;MDC-3;SCC-S;TNFAIP;TNFAIP8;GG2-1;MDC-3.13;NDED;SCC-S2;SCCS2;GG2 1;Head and neck tumor and metastasis-related protein;NF-kappa-B-inducible DED-containing protein;SCC S2;TFIP8;TNF alpha-induced protein 8;TNF induced protein;TNFAIP 8;TNF-induced protein GG2-1;Tumor necrosis factor alpha induced protein 8;Tumor necrosis factor alpha-induced protein 8
• Area di ricerca: Immunology;Cell Biology;Signal Transduction;Cancer