This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

Dettagli prodotto

• Codice: AN200118P_100μL
• Marca: Elabscience
• Specie target: Human;Cynomolgus
• Host: Mouse
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
• Isotipo: IgG1
• Clonalità: Monoclonal
• Clone: 7A12
• Coniugazione: Unconjugated
• Applicazione: IHC-P;FCM
• Diluizione: IHC-P 1:30-1:100;FCM 1:25-1:100;
• Simbolo target: CD68
• Ig target: SRD;LAMP;DKFZp686M;MACROPHAGE ANTIGEN CD;CD68 antigenmacrophage antigen CD;Scavenger receptor class D member;SR-D;SCARD;CD68;GP110;LAMP4;SCARD1;CD 68;CD68 antigen;CD68 antigenmacrophage antigen CD68;CD68 molecule;DKFZp686M18236;gp11;MACROPHAGE ANTIGEN CD68;Macrophage antigen CD68 (microsialin);Macrosialin;Scavenger receptor class D member 1;SRD1;SR-D1;gp110;CD 68;CD68;CD68 antigen;CD68 molecule;CD68;DKFZp686M18236;gp11;Gp110;LAMP4;Macrophage antigen CD68 (microsialin);MACROPHAGE ANTIGEN CD68;Macrosialin;SCARD1;Scavenger receptor class D member 1
• Area di ricerca: Immunology