Pepsiongen II is a zymogen secreted by the chief cells of the gastric glands and converted into pepsin in the presence of gastric acid or of pepsin itself. Among endoscopy clinic patients, PGII is a sensitive marker for extension of nonatrophic gastritis toward the corpus. PGI is a stable biomarker in assessment of fundic atrophy and has similar accuracy to PGI/PGII ratio among populations with prevalent nonatrophic pangastritis. Research also showed that decreased PG I level and PG I/II ratio are risk factors for gastric cancer. Combined use of serum PG I level and PG I/II ratio may help the early diagnosis of gastric cancer.
Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotipo: IgG1
Clonalità: Monoclonal
Clone: 6F7
Coniugazione: Unconjugated
Applicazione: IHC-P
Diluizione: IHC-P 1:50-1:200;
Simbolo target: PGC
Ig target: PGC;PEPC;PGII;gastricsin;Pepsinogen C;Pepsinogen II;PGC p
Area di ricerca:Signal Transduction;Cancer;Microbiology;Metabolism
Newsletter TEMA RICERCA
Ricevi aggiornamenti rilevanti per il tuo lavoro
Inserisci la tua e-mail e seleziona le aree di interesse per ricevere le ultime novità, approfondimenti e promozioni.
