This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.

Dettagli prodotto

• Codice: AN200131P_100μL
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
• Isotipo: IgG2a
• Clonalità: Monoclonal
• Clone: 11A2
• Coniugazione: Unconjugated
• Applicazione: FCM;ICC/IF
• Diluizione: ICC/IF 1:20-1:100;FCM 1:25-1:100;
• Simbolo target: RHOA
• Ig target: ARH;RHOH;ARH12;ARHA;RHO12;RHOH12;Rho;RHOA;EDFAOB;ARH12;EDFAOB;RHO12;RHOH12;Aplysia ras related homolog 12;H 12;H12;Oncogene RHO H12;ras homolog family member A;Ras homolog gene family member A;Rho A;Rho cDNA clone 12;RHO H12;Small GTP binding protein Rho A;Transforming protein Rho A;Transforming protein RhoA
• Area di ricerca: Signal Transduction;Cancer