This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotipo: IgG1
Clonalità: Monoclonal
Clone: 11B8
Coniugazione: Unconjugated
Applicazione: IHC-P
Diluizione: IHC-P 1:30-1:100;
Simbolo target: MSLN
Ig target: CAK;MSLN;MPF;SMRP;CAK1;CAK1 antigen;Megakaryocyte potentiating factor;mesothelin;Pre-pro-megakaryocyte-potentiating factor;SMR;soluble MPF mesothelin related protein;CAK 1;C-ERC/mesothelin;C-ERC/MSLN;cleaved form;Mesothelin isoform 1 precursor;N-ERC/mesothelin;N-ERC/MSLN;Pre pro megakaryocyte potentiating factor
Area di ricerca:Tags & Cell Markers;Cancer
Newsletter TEMA RICERCA
Ricevi aggiornamenti rilevanti per il tuo lavoro
Inserisci la tua e-mail e seleziona le aree di interesse per ricevere le ultime novità, approfondimenti e promozioni.