This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP5 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

Dettagli prodotto

• Codice: AN300059P_100μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
• Isotipo: IgG
• Clonalità: Rabbit Monoclonal
• Clone: 6A2
• Coniugazione: Unconjugated
• Applicazione: WB;IP
• Diluizione: WB 1:500-1:2000;IP 0.5-2 μL/mg of lysate
• Simbolo target: BID
• Ig target: BID;FP497;BH3-Interacting Domain Death Agonist;p22 BID
• Area di ricerca: Cell Biology;Cancer;Metabolism