This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307).

Dettagli prodotto

• Codice: AN300064P_100μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
• Isotipo: IgG
• Clonalità: Rabbit Monoclonal
• Clone: 6A7
• Coniugazione: Unconjugated
• Applicazione: IP
• Diluizione: IP 1-2 μL/mg of lysate
• Simbolo target: IGFBP7
• Ig target: MAC;IBP;FSTL;IGF-binding protein;Insulin-like growth factor-binding protein;IGFBPRP;IGFBP-rP;IGFBP7;AGM;FSTL2;IBP-7;IGFBP-7;IGFBP-7v;IGFBPRP1;MAC25;PSF;RAMSVPS;TAF;IGF-binding protein 7;IGFBP-rP1;Insulin-like growth factor-binding protein 7;MAC25 protein;Tumor-derived adhesion factor;Angiomodulin;IBP7;IGF binding protein 7;IGFBP rP1;Insulin like growth factor binding protein 7;PGI2 stimulating factor;PGI2-stimulating factor;Prostacyclin stimulating factor;Prostacyclin-stimulating factor
• Area di ricerca: Signal Transduction;Cancer