The human polymeric immunoglobulin receptor (pIgR; also known as membrane secretory component) is an approximately 100 kDa type I transmembrane glycoprotein that is synthesized as a 764 amino acid (aa) precursor. It includes a signal sequence (aa 1-18), an extracellular region (aa 19-638), a transmembrane segment (aa 639-661), and a cytoplasmic domain (aa 662-764) . The extracellular region consists of five Ig-like domains and a sixth non-Ig domain that connects to the membrane region. pIgR is expressed on secretory epithelial cells of exocrine tissues. Immunoglobulin isotypes consist of two heavy (H) and two light (L) chains. F

Dettagli prodotto

• Codice: AN300080P_20μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
• Isotipo: IgG
• Clonalità: Rabbit Monoclonal
• Clone: 12G8
• Coniugazione: Unconjugated
• Applicazione: IHC-P;ICC/IF
• Diluizione: IHC-P 1:50-1:200;ICC/IF 1:20-1:100;
• Simbolo target: PIGR
• Ig target: Hepatocellular carcinoma-associated protein TB;PIGR;Polymeric immunoglobulin receptor;Hepatocellular carcinoma-associated protein TB6;Secretory component;Poly-Ig receptor
• Area di ricerca: Immunology