This gene encodes a protein containing tetratricopeptide repeat and a U-box that functions as a ubiquitin ligase/cochaperone. The encoded protein binds to and ubiquitinates shock cognate 71 kDa protein (Hspa8) and DNA polymerase beta (Polb), among other targets. Mutations in this gene cause spinocerebellar ataxia, autosomal recessive 16. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 2.

Dettagli prodotto

• Codice: AN300116P_100μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
• Isotipo: IgG
• Clonalità: Rabbit Monoclonal
• Clone: 9D2
• Coniugazione: Unconjugated
• Applicazione: WB;FCM;ICC/IF;IP
• Diluizione: WB 1:500-1:2000;FCM 1:100-1:500;ICC/IF 1:100-1:500;IP 1-4 μL/mg of lysate
• Simbolo target: STUB1
• Ig target: STUB;SCAR;UBOX;Antigen NY-CO;CLL-Associated Antigen KW;STIP1 Homology and U Box-Containing Protein;NY-CO;HSPABP;SDCCAG;STUB1;CHIP;HSPABP2;NY-CO-7;SCAR16;SDCCAG7;UBOX1;Antigen NY-CO-7;Carboxy Terminus of Hsp70-Interacting Protein;CLL-Associated Antigen KW-8;E3 Ubiquitin-Protein Ligase CHIP;STIP1 Homology and U Box-Containing Protein 1;PP1131;STIP1 homology and U-box containing protein 1
• Area di ricerca: Signal Transduction;Epigenetics and Nuclear Signaling