This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

Dettagli prodotto

• Codice: AN300133P_100μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
• Isotipo: IgG
• Clonalità: Rabbit Monoclonal
• Clone: 3G3
• Coniugazione: Unconjugated
• Applicazione: IHC-P
• Diluizione: IHC-P 1:100-1:500;
• Simbolo target: Sox2
• Ig target: SOX;ANOP;MCOPS;SRY-box;ANOP3;MCOPS3;SOX2;SRY-box 2;cb236;Delta EF2a;lcc;MGC148683;MGC2413;RGD1565646;Sex determining region Y box 2;SOX 2;SRY (sex determining region Y) box 2;SRY box containing gene 2;SRY related HMG box 2;SRY related HMG box gene 2;Transcription factor SOX 2;Transcription factor SOX-2;ysb;ANOP3;MCOPS3;Sox2;SRY-box 2
• Area di ricerca: Neuroscience;Epigenetics and Nuclear Signaling;Stem Cells;Developmental Biology