The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 1-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.
Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotipo: IgG
Clonalità: Rabbit Monoclonal
Clone: 3F5
Coniugazione: Unconjugated
Applicazione: IHC-P
Diluizione: IHC-P 1:100-1:500;
Simbolo target: ACOX1
Ig target: ACOX1;ACOX;PALMCOX;SCOX;Acyl CoA oxidase 1 palmitoyl;Acyl CoA oxidase straight chain;AOX;EC 1.3.3.6;Palmitoyl CoA oxidase;Palmitoyl-CoA oxidase;Peroxisomal acyl coenzyme A oxidase 1;Peroxisomal acyl-coenzyme A oxidase 1;Peroxisomal fatty acyl CoA oxidase;Straight chain acyl CoA oxidase;Straight-chain acyl-CoA oxidase
Area di ricerca:Signal Transduction;Cardiovascular;Cancer;Metabolism
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