Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR2 degradation. Controls PGR protein levels through a similar mechanism.

Dettagli prodotto

• Codice: AN300233P_100μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
• Isotipo: IgG
• Clonalità: Rabbit Monoclonal
• Clone: 4F3
• Coniugazione: Unconjugated
• Applicazione: IHC-P
• Diluizione: IHC-P 1:500-1:2000;
• Simbolo target: CUEDC2
• Ig target: MGC;CUE domain containing;CUE domain-containing protein;Chromosome 10 open reading frame;HOYS;CUED;CUEDC;bA18I;C10orf;OTTHUMP;CUEDC2;C10orf66;bA18I14.5;Chromosome 10 open reading frame 66;CUE domain containing 2;CUE domain-containing protein 2;CUED2;MGC2491;OTTHUMP00000020368;HOYS6
• Area di ricerca: Epigenetics and Nuclear Signaling;Signal Transduction