The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 4. Alternative splicing results in multiple transcript variants.
Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotipo: IgG
Clonalità: Monoclonal
Clone: 11B4
Coniugazione: Unconjugated
Applicazione: WB;FCM;ICC/IF;IP
Diluizione: WB 1:500-1:1000;FCM 1:100-1:500;ICC/IF 1:100-1:500;IP 0.2-1 μL/mg of lysate
Simbolo target: MAX
Ig target: bHLHd;MAX;bHLHd4;Class D Basic Helix-Loop-Helix Protein 4;Myc-Associated Factor X;Protein Max
Area di ricerca:Epigenetics and Nuclear Signaling
Newsletter TEMA RICERCA
Ricevi aggiornamenti rilevanti per il tuo lavoro
Inserisci la tua e-mail e seleziona le aree di interesse per ricevere le ultime novità, approfondimenti e promozioni.
