Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.

Dettagli prodotto

• Codice: AN300279P_100μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
• Isotipo: IgG
• Clonalità: Rabbit Monoclonal
• Clone: 14B8
• Coniugazione: Unconjugated
• Applicazione: IHC-P
• Diluizione: IHC-P 1:100-1:500;
• Simbolo target: GCSH
• Ig target: GCSH;GCE;NKH;Glycine cleavage system H protein;Glycine cleavage system H protein mitochondrial;Glycine cleavage system protein H;Glycine cleavage system protein H (aminomethyl carrier);Lipoic acid containing protein;mitochondrial;Mitochondrial glycine cleavage system H protein
• Area di ricerca: Tags & Cell Markers;Signal Transduction;Metabolism