This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv1 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described.

Dettagli prodotto

• Codice: AN300283P_100μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
• Isotipo: IgG
• Clonalità: Rabbit Monoclonal
• Clone: 10C4
• Coniugazione: Unconjugated
• Applicazione: IHC-P
• Diluizione: IHC-P 1:250-1:1000;
• Simbolo target: KCNIP3
• Ig target: KCNIP;KCHIP;KCNIP3;CSEN;DREAM;KCHIP3;4933407H12Rik;A type potassium channel modulatory protein 3;AI413860;A-type potassium channel modulatory protein 3;Calsenilin;DRE antagonist modulator;DRE-antagonist modulator;EF hand transcription factor;KCHIP 3;KCNIP 3;Kv channel interacting protein 3;Kv channel-interacting protein 3;MGC18289;Potassium channel interacting protein 3;R74849
• Area di ricerca: Cardiovascular;Neuroscience;Signal Transduction