This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.

Dettagli prodotto

• Codice: AN300314P_100μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
• Isotipo: IgG
• Clonalità: Monoclonal
• Clone: 8D1
• Coniugazione: Unconjugated
• Applicazione: WB;IP
• Diluizione: WB 1:500-1:1000;IP 1-2 μL/mg of lysate
• Simbolo target: SerpinF2
• Ig target: PDGFA-Associated Protein;PDAP;HASPP;SERPINF;SERPINF2;A2AP;AAP;ALPHA-2-PI;API;PLI;PAP1;Alpha 2-antiplasmin;Alpha-2-plasmin inhibitor;HASPP28;PAP;PDAP1;PDGFA-Associated Protein 1;plasmin inhibitor;α2-antiplasmin;Alpha 2 antiplasmin;Alpha 2 antiplasmin pigment epithelium derived factor;Alpha 2 AP;ALPHA 2 PI;Alpha 2 plasmin inhibitor;Alpha 2 plasmin inhibitor deficiency;Alpha-2-antiplasmin;Alpha-2-AP;Antiplasmin deficiency;clade F;clade F (alpha 2 antiplasmin pigment epithelium derived factor) member 2;isoform CRA_c;member 2;Plasmin inhibitor deficiency;Serine (or cysteine) peptidase inhibitor;Serine (or cysteine) proteinase inhibitor;Serine or cysteine peptidase inhibitor clade F member 2;Serpin F2;Serpin peptidase inhibitor;Serpin peptidase inhibitor clade F
• Area di ricerca: Cardiovascular;Cell Biology