The p53 tumor suppressor protein is a multi-functional transcription factor that regulates cellular decisions regarding proliferation, cell cycle checkpoints, and apoptosis. The importance of p53 is underscored by its mutation in over 50% of human cancers. Mice that lack one or both copies of p53 also showed an increased incidence of tumors, which makes the p53 deficient mouse a model system for studying cancer generation and progression.

Dettagli prodotto

• Codice: AN300367L_20μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
• Isotipo: IgG
• Clonalità: Monoclonal
• Clone: 11A5
• Coniugazione: Unconjugated
• Applicazione: WB
• Diluizione: WB 1:1000-1:5000
• Simbolo target: TP53
• Ig target: BCC;LFS;TRP;BMFS;Antigen NY-CO;Tumor protein;Phosphoprotein p;Tumor suppressor p;Mutant tumor protein;Cellular tumor antigen p;Transformation related protein;BCC7;LFS1;P53;TRP53;TP53;BMFS5;Antigen NY-CO-13;Cellular tumor antigen p53;FLJ92943;Mutant tumor protein 53;p53 tumor suppressor;Phosphoprotein p53;Transformation related protein 53;Tumor protein 53;Tumor protein p53;Tumor suppressor p53;BCC7;LFS1;P53;TRP53;tumor protein p53;Antigen NY-CO-13;BCC7;Cellular tumor antigen p53;FLJ92943;LFS1;Mutant tumor protein 53;p53;p53 tumor suppressor;P53;Phosphoprotein p53;Tp53;Transformation related protein 53;TRP53;Tumor protein 53;Tumor protein p53;Tumor suppressor p53
• Area di ricerca: Cell Biology;Epigenetics and Nuclear Signaling;Cancer