Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

Codice: AN300385L_20μL | Marca: Elabscience | Confezionamento: 20μL

Specie: HumanIsotipo: IgGClone: 11G9Coniugazione: Unconjugated
Dettagli prodotto
  • Codice: AN300385L_20μL
  • Marca: Elabscience
  • Specie target: Human
  • Host: Rabbit
  • Concentrazione: 1 mg/mL
  • Link: Apri link
  • Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
  • Isotipo: IgG
  • Clonalità: Monoclonal
  • Clone: 11G9
  • Coniugazione: Unconjugated
  • Applicazione: WB
  • Diluizione: WB 1:1000-1:10000
  • Simbolo target: KDR
  • Ig target: Krd;VEGF Receptor;Fetal liver kinase;Protein-tyrosine kinase receptor flk;Vascular endothelial growth factor receptor;sVEGFR;VEGF R;6130401C;FLK;CD309;FLK1;VEGFR;VEGFR2;VEGF Receptor 2;KDR;6130401C07;Fetal liver kinase 1;FLK-1;Kinase insert domain receptor;Krd-1;Ly73;Protein-tyrosine kinase receptor flk-1;sVEGFR-2;Vascular endothelial growth factor receptor 2;VEGF R2;VEGFR-2;KDR
  • Area di ricerca: Cardiovascular;Microbiology;Signal Transduction;Stem Cells;Cancer;Metabolism