This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Dettagli prodotto

• Codice: AN300386L_100μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
• Isotipo: IgG
• Clonalità: Monoclonal
• Clone: 11G10
• Coniugazione: Unconjugated
• Applicazione: WB
• Diluizione: WB 1:1000-1:10000
• Simbolo target: SRC
• Ig target: THC;ASV;SRC1;THC6;c-SRC;p60-Src;SRC;pp60c-src;Proto-oncogene c-Src;Proto-oncogene tyrosine-protein kinase Src;Avian sarcoma virus;c SRC;CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA;cSrc;EC 2.7.10.2;Neuronal CSRC tyrosine specific protein kinase;Neuronal SRC;Oncogene SRC;OTTHUMP00000174476;OTTHUMP00000174477;p60 Src;p60Src;pp60c src;pp60csrc;Proto oncogene tyrosine protein kinase Src;Protooncogene SRC;Protooncogene SRC Rous sarcoma;SRC Oncogene;SRC proto oncogene non receptor tyrosine kinase;Tyrosine kinase pp60c src;Tyrosine protein kinase SRC 1;Tyrosine protein kinase SRC1;v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog;V src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog (avian);v src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog avian
• Area di ricerca: Signal Transduction;Epigenetics and Nuclear Signaling;Cancer