The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.

Dettagli prodotto

• Codice: AN300401P_100μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
• Isotipo: IgG
• Clonalità: Monoclonal
• Clone: 9D8
• Coniugazione: Unconjugated
• Applicazione: IHC-P
• Diluizione: IHC-P 1:50-1:200
• Simbolo target: STK4
• Ig target: STK;MST;YSK;KRS;BCC;LFS;TRP;Antigen NY-CO;Tumor protein;Tumor protein p;Phosphoprotein p;Tumor suppressor p;Mutant tumor protein;serine/threonine kinase;Cellular tumor antigen p;Transformation related protein;STK4;KRS2;MST1;YSK3;serine/threonine kinase 4;Antigen NY-CO-13;BCC7;Cellular tumor antigen p53;FLJ92943;LFS1;Mutant tumor protein 53;p53;p53 tumor suppressor;Phosphoprotein p53;TIIAC;Tp53;Transformation related protein 53;TRP53;Tumor protein 53;Tumor protein p53;Tumor suppressor p53;KRS2;MST1;serine/threonine kinase 4;YSK3;Kinase responsive to stress;Mammalian STE20 like protein kinase 1;Mammalian STE20-like protein kinase 1;Mammalian sterile 20 like 1;MST-1;Serine/threonine protein kinase Krs 2;Serine/threonine-protein kinase 4;Serine/threonine-protein kinase Krs-2;STE20 like kinase MST1;STE20-like kinase MST1
• Area di ricerca: Signal Transduction;Cardiovascular