The hypoxia-inducible transcription factor 1 alpha (HIF-1 alpha ) is the regulated member of the transcription factor heterodimer HIF-1. HIF-1 binds to hypoxia-response elements (HREs) in the promoters of many genes involved in adapting to an environment of insufficient oxygen or hypoxia. Hypoxic tissue environments occur in vascular and pulmonary diseases as well as cancer, which illustrates the broad impact of gene regulation by HIF-1 alpha.

Dettagli prodotto

• Codice: AN300409P_100μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
• Isotipo: IgG
• Clonalità: Monoclonal
• Clone: 5D7
• Coniugazione: Unconjugated
• Applicazione: ICC/IF
• Diluizione: ICC/IF 1:20-1:100
• Simbolo target: HIF1A
• Ig target: HIF;MOP;PASD;member of PAS protein;hypoxia inducible factor;bHLHe;HIF-1A;HIF1-ALPHA;HIF-1alpha;HIF1A;bHLHe78;HIF1;MOP1;PASD8;HIF-1-alpha;hypoxia inducible factor 1;alpha subunit;basic helix-loop-helix transcription factor;hypoxia-inducible factor 1-alpha;HIF 1alpha;member of PAS protein 1;ARNT interacting protein;ARNT-interacting prot;alpha subunit (basic helix loop helix transcription factor);ARNT-interacting protein;Basic helix loop helix PAS protein MOP1;Basic-helix-loop-helix-PAS protein MOP1;Class E basic helix-loop-helix protein 78;HIF 1A;HIF1 A;HIF1 Alpha;Hypoxia inducible factor 1 alpha;Hypoxia inducible factor 1 alpha isoform I.3;Hypoxia inducible factor 1 alpha subunit;Hypoxia inducible factor 1 alpha subunit basic helix loop helix transcription factor;Hypoxia inducible factor1alpha;Member of PAS superfamily 1;Member of the PAS Superfamily 1;MOP 1;PAS domain-containing protein 8;PASD 8
• Area di ricerca: Cardiovascular;Epigenetics and Nuclear Signaling;Cancer;Metabolism