This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

Dettagli prodotto

• Codice: AN300411P_100μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
• Isotipo: IgG
• Clonalità: Monoclonal
• Clone: 5D10
• Coniugazione: Unconjugated
• Applicazione: WB;IP
• Diluizione: WB 1:500-1:2000;IP 1-4 μL/mg of lysate
• Simbolo target: NFKBIA
• Ig target: EDAID;MAD;IKBA;MAD-3;NFKBI;IKB alpha;NFKBIA;EDAID2;I kappa B alpha;IkappaBalpha;I-kappa-B-alpha;IKBalpha;IkB-alpha;MAD 3;NF kappa B inhibitor alpha;MAD3;alpha;Major histocompatibility complex enhancer-binding protein MAD3;NF-kappa-B inhibitor alpha;Nuclear factor of kappa light chain gene enhancer in B cells;Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor alpha;nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor;pIκBα
• Area di ricerca: Signal Transduction;Epigenetics and Nuclear Signaling;Cancer;Immunology