This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.

Dettagli prodotto

• Codice: AN300447P_100μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
• Isotipo: IgG
• Clonalità: Monoclonal
• Clone: 2D10
• Coniugazione: Unconjugated
• Applicazione: WB
• Diluizione: WB 1:500-1:1000
• Simbolo target: LSM1
• Ig target: LSM;U6 snRNA-Associated Sm-Like Protein LSm;LSM1;CASM;YJL124C;Cancer-Associated Sm-Like;Small Nuclear Ribonuclear CaSm;U6 snRNA-Associated Sm-Like Protein LSm1
• Area di ricerca: Tags & Cell Markers;Epigenetics and Nuclear Signaling