ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity.

Dettagli prodotto

• Codice: AN300450P_100μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
• Isotipo: IgG
• Clonalità: Monoclonal
• Clone: 5H6
• Coniugazione: Unconjugated
• Applicazione: ICC/IF
• Diluizione: ICC/IF 1:20-1:100
• Simbolo target: ARL2BP
• Ig target: ARL2BP;BART;BART1;RP66;ADP ribosylation factor like 2 binding protein;ADP-ribosylation factor-like protein 2-binding protein;AR2BP;Arf like 2 binding protein BART1;ARF-like 2-binding protein;ARL2 binding protein;ARL2BP protein;Binder of ARF2 protein 1;Binder of Arl Two;Binder of Arl2;Retinitis pigmentosa 66 (autosomal recessive)
• Area di ricerca: Signal Transduction